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Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers. Its products candidatures include the ZN-c3, an inhibitor of WEE1, a protein tyrosine kinase for the treatment of inhibitor for advanced solid tumors and hematological malignancies; in Phase 2 clinical trial as a monotherapy for the treatment of uterine serous carcinoma indications; Phase 2 clinical trial in Cyclin E1 driven high-grade serous ovarian cancer, fallopian tube, or primary peritoneal cancer; Phase 1/2 clinical trial in combination with PARPi for platinum-resistant ovarian cancer; Phase 1b clinical trial in combination with chemotherapy in platinum-resistant ovarian, and peritoneal or fallopian tube cancer; Phase 1/2 clinical trial in combination with chemotherapy in relapsed or refractory osteosarcoma; Phase 1/2 clinical trial with encorafenib and cetuximab for mutant metastatic colorectal cancer; and Phase 1/2 clinical trial in combination with chemotherapy in pancreatic cancer. The company’s products pipeline also includes ZN-d5, an oral small molecule inhibitor of B-cell lymphoma 2, for hematological malignancies and related disorders; and BCL-xL heterobifunctional degrader, a member of the anti-apoptotic BCL-2 proteins, for solid tumors and hematological malignancies. Zentalis Pharmaceuticals, Inc. has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC; Pfizer, Inc.; Zentera Therapeutics; Dana-Farber; and GlaxoSmithKline plc. The company was incorporated in 2014 and is headquartered in New York, New York.
नाम | आयु | पहले | शीर्षक |
---|---|---|---|
Kimberly Lynn Blackwell | 53 | 2020 | CEO & Director |
David Michael Johnson | 58 | 2020 | Independent Chairman of the Board |
Cameron S. Gallagher | 54 | 2014 | Co-Founder, President, Interim CFO, Interim Treasurer & Director |
Kwok-Kin Wong | - | - | Member of Scientific Advisory Board |
Karan S. Takhar | 32 | 2017 | Independent Director |
Enoch K. Kariuki | 42 | 2021 | Independent Director |
Anthony G. Letai | - | - | Member of Scientific Advisory Board |
Ross L. Levine | 51 | - | Member of Scientific Advisory Board |
Adam Schayowitz | - | 2022 | Member of Scientific Advisory Board |
Jan Skvarka | 56 | 2022 | Independent Director |
Funda Meric-Bernstam | - | 2023 | Member of Scientific Advisory Board |
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